If you are unable to fertilize your neighbor's farm, it is normally due to one of the following reasons.
  1. All the crops on your neighbor's farm have already been fertilized by other neighbors.
  2. Your neighbor's crops are all already mature and ready for harvest.
  3. There are no crops planted on the neighbor's farm
 

If a neighbor has been offline for 3 days or more, you can tap on the horn to call him/her back to the game.
Yellow color horn = neighbor hasn't logged in between 3-14 days.
Red color horn = neighbor hasn't logged in for more than 14 days.